Those with the Burning Crusade, a level 68 or higher character, and Alchemy at 325 skill can embark on a question to gain a specialization in Alchemy. You can only learn ONE specialization and can¡¯t switch without dropping Alchemy (and losing all of your skill, recipes, and discoveries). If you do drop Alchemy to switch then note you won¡¯t have to do the quest for the other specializations.
Blizzard has mentioned the rate to create additional items is at around 10-15%. You can end up getting 5 additional items in the creation of the same item. All of the items are duplicates of whatever you are creating. In most cases, you can only get additional items off of high level recipes.
Master of Elixirs
Allows an Alchemist to sometimes create more than one (up to 5) elixirs. Flasks are considered Elixirs, making this a very good specialization for any raiding guild Alchemists. For the more casual players who focus on potions or transmutes for cash then this wouldn¡¯t be that great.
To gain a mastery of elixirs travel to Shattrath city and speak with Lorokeen. You¡¯ll need 10 Essence of Infinity, 5 elixirs of major defense, 5 elixirs of mastery, and 5 elixirs of major agility. Return with the items and you will have gained the mastery of elixirs.
Master of Potions
Allows an Alchemist to sometimes create more than one (up to five) potions. This is a great mastery for anyone who brews potions often for PvP or to sell on the auction house. If you find yourself doing elixirs more often for your guild or for the buffs then this wouldn¡¯t be that great of an idea.
To gain a mastery of potions travel to Cenarion Refuge in Zangarmarsh. Find Lauranna Thar¡¯well and take on her quest. She¡¯ll want the Botanist¡¯s Field Guide, 5 Super Healing Potions, 5 Super Mana Potions, and 5 Major Dreamless Sleep potions.
Master of Transmutation
Allows an Alchemist to get greater results when transmuting which basically means you can get up to five additional items during a transmute. Very useful for those who do transmuting often to take inexpensive metals/essences and turn them into something more profitable.
If you want to gain a mastery of transmutation, head to Stormspire in Netherstorm. There Zarevhi waits and he wants four Primal Mights.